CCL2 anticorps

N° du produit ABIN7145970

L’anticorps Souris Monoclonal anti-CCL2 a été validé pour IHC et ELISA. Il convient pour détecter CCL2 dans des échantillons de Humain.

Aperçu rapide pour CCL2 anticorps (ABIN7145970)

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: 3D2E5

Détail du produit anti-CCL2 anticorps

Fonction: CCL2 Monoclonal Antibody

Purification: Protein G purified

Pureté: >95 %

Immunogène: Recombinant Human C-C motif chemokine 2

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CCL2

Antigène: CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))

Autre désignation: CCL2

Sujet:

Background: Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. [1] "Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)."Furutani Y., Nomura H., Notake M., Oyamada Y., Fukui T., Yamada M., Larsen C.G., Oppenheim J.J., Matsushima K.Biochem. Biophys. Res. Commun. 159:249-255(1989) [2] "The human homolog of the JE gene encodes a monocyte secretory protein."Rollins B.J., Stier P., Ernst T., Wong G.G.Mol. Cell. Biol. 9:4687-4695(1989) [3] "Human monocyte chemoattractant protein-1 (MCP-1). Full-length cDNA cloning, expression in mitogen-stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE."Yoshimura T., Yuhki N., Moore S.K., Appella E., Lerman M.I., Leonard E.J.FEBS Lett. 244:487-493(1989)

Aliases: Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,Monocyte chemotactic protein 1,Monocyte secretory protein JE,Small-inducible cytokine A2,CCL2,MCP1, SCYA2

UniProt: P13500

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, Phosphorylation & l'infection par le SRAS-CoV-2